FIREFIGHTERS FACE A HIGHER BRAIN CANCER RISK CAUSED BY CHEMICAL EXPOSURE

Gene mutations caused by exposure to certain chemical compounds have been linked to the development of gliomas, the most common type of malignant brain tumor.

New research published online in Cancer, reveals that among patients with gliomas, these mutations are more common in firefighters than in individuals with other occupations.

The gene mutations are associated with exposure to haloalkanes, which are used in flame retardants, fire extinguishants, refrigerants, and other products.

Among non-firefighters, the mutational signature was more likely in those with occupations that also possibly exposed them to haloalkanes, such as car painting and machine maintenance.

Source 👉 Glioma mutational signatures associated with haloalkane exposure are enriched in firefighters, Cancer (2025)