THE PERFECT DECEPTION: HOW CANCER STEALS THE MANUAL OF LIFE TO SURVIVE
To grow, a tumor must achieve the impossible: convince our immune system NOT to destroy it. How does it do it? With an ancient and ingenious theft. It browses an archive hidden in our own DNA. It reactivates the same genetic programs that allowed us, as embryos, to build the placenta, invade the uterus, create […]
A New Era of Immunotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma
The standard of care for locally advanced HNSCC has remained unchanged for decades. However, 2 landmark studies presented at the 2025 ASCO Annual Meeting may signal a pivotal shift in the management of locally advanced, resectable HNSCC. Key Points: The standard of care for locally advanced head and neck squamous cell carcinoma (HNSCC) has remained […]
HOW CAR-T CELLS ARE ENGINEERED TO FIGHT CANCER
HOW CAR-T CELLS ARE ENGINEERED TO FIGHT CANCER A chimeric antigen receptor (CAR) sprouts from the surface of a genetically reengineered white blood cell. The receptor is a manufactured protein, and designed by molecular biologists to seek out and interact with specific antigens appearing on cancer cells. Now empowered with CAR, these killer T-cells are […]
GIRL TREATED WITH CAR-T FOR NEUROBLASTOMA, IS STILL ALIVE AND HEALTHY 19 YEARS AFTER TREATMENT
GIRL TREATED WITH CAR-T FOR NEUROBLASTOMA, IS STILL ALIVE AND HEALTHY 19 YEARS AFTER TREATMENT In a recent study published in Nature Medicine, researchers report the successful treatment of a neuroblastoma patient with chimeric antigen receptor (CAR) T-cell therapy. A woman, now twenty-three years old and with two children, treated in 2006, with a pioneering […]